What’s the best way to handle a clogged drain in your home or place of business? For many people, the first step for getting rid of a clog is to pour some off-the-shelf drain cleaner down the drain and hope for the best. If you’re a do-it-yourselfer, you could waste precious time and experience plenty of frustration while trying to repair the problem on your own. But even if your efforts are initially successful, you might only receive temporary relief from your clogged drain issue.